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ZYMOX Rinse with Vitamin D3 produces a powerful protective barrier against minor skin inflammations and surface irritations due to bacterial and fungal microbes. The LP3 Enzyme System with Vitamin D3 is antibacterial and antifungal. For best results, wash first with ZYMOX Shampoo and use as a leave-in rinse for residual effectiveness. Can also be safely applied full strength directly to most problematic areas. Bio-active enzymes have been shown to be effective against: - Pyotraumatic Dermatitis - Trichopyton - Pseudomonas - Impetigo - Candida Albicans - Staphylococcus - Bodyfold Pyoderma - Malassezia - Microsporum Can be used as a leave-on rinse for extended benefits. Safe for use of all ages of cats and dogs. For topical use only, although it is 100% safe if ingested. Contains no harsh detergents, pesticides, artificial coloring agents or petroleum by-products. Made in the USA.